27th June 2017

An exploration tool for chloroplast metabolism connected with other cell compartments

Cell metabolism is extremely complex especially in plants but as most molecular components are now well characterized it appears possible in a near future to predict its behavior. However, this can only be done thanks to dedicated software. To this purpose we developed a web-application dedicated to the model plant Arabidopsis thaliana (freely available at http://chlorokb.fr ). The main originality of ChloroKB is a graphical representation of the cellular context (subcellular localization of proteins and metabolites, proteins inside protein-protein complexes, fine regulations). Thanks to this tool it is now possible to explore interactively the metabolic network of the chloroplast and […]
20th June 2017

How phytoplankton rule the oceans

Photosynthesis is a unique biological process that has permitted the colonization of land and sea by plants and phytoplankton respectively. While the mechanisms of photosynthesis in plants are well understood, scientists are only now beginning to elucidate how the process developed in phytoplankton. In collaboration with scientists from several thylakoid architecture optimizes photosynthesis in countries, researchers from the Cell and Plant Physiology Laboratory (CNRS/CEA/UGA/Inra), the Institut de Biologie Structurale (CNRS/CEA/UGA), the LEMMA Advanced Electron Microscopy Laboratory (CEA/UGA), and the Laboratory of Membrane and Molecular Physiology of the Chloroplast (CNIRS/UPMC) have proposed a structural model of the photosynthetic process in phytoplankton, […]
22nd September 2016

A blue-light photoreceptor mediates the feedback regulation of photosynthesis – article in Nature!

Green microalgae, the ancestors of land plants, are microscopic organisms mainly living in the planet waters. Like plants, they are able of performing photosynthesis, a complex metabolic process that converts CO2 into biomass and oxygen using the energy of sunlight. Light is not only the source of energy that fuels photosynthesis but also acts as source of information. Thanks to specific sensors, called photoreceptors, algae respond to the light colour moving towards or against the light (phototaxis), regulating their cell division and other fundamental processes. When light intensity becomes very strong (i.e. under full sunlight) it can become toxic, producing reactive oxygen species and cell […]
26th January 2016

Explore the molecular diversity of glycolipids in oleaginous microalgae

​​​​Researchers at the Cell & Plant Physiology Laboratory are studying diatoms glycerolipids, some of which are called oleaginous and of interest since they should allow industrial developments (biofuels). By screening small molecules, they demonstrated that the metabolic pathways leading to these glycerolipids could be oriented to favor the accumulation of oil they and deposit a patent.​​​​​ References Abida H, Dolch LJ, Meï C, Villanova V, Conte M, Block MA, Finazzi G, Bastien O, Tirichine L, Bowler C, Rébeillé F, Petroutsos D, Jouhet J and Maréchal E Membrane glycerolipid remodeling triggered by nitrogen and phosphorus starvation in Phaeodactylum tricornutum. Plant Physiology, […]
16th July 2015

Energetic coupling between photosynthesis and respiration

As part of an international collaboration, a French team has revealed the cellular mechanisms behind the impressive photosynthetic capacity of unicellular marine organisms: Diatoms.​​ References Bailleul B, Berne N, Murik O, Petroutsos D, Prihoda J, Tanaka A, Villanova V, Bligny R, Flori S, Falconet D, Krieger-Liszkay A, Santabarbara S, Rappaport F, Joliot P, Tirichine L, Falkowski PG, Cardol P, Bowler C and Finazzi G Energetic coupling between plastids and mitochondria drives CO2 assimilation in diatoms. Nature, 2015
15th November 2013

The missing link of the chemiosmotic theory

An international collaboration has enabled researchers at the Cell & Plant Physiology Laboratory to highlight the action of the TPK3 potassium channel on the use of light by the electron transfer, and thus the survivability of the plant. References Carraretto L, Formentin E, Teardo E, Checchetto V, Tomizioli M, Morosinotto T, Giacometti GM, Finazzi G and Szabó I A thylakoid-located two-pore Potassium channel controls photosynthetic light utilization in plants. Science, 2013
27th June 2013

Photoprotection in microalgae

Researchers at the Plant & Cellular Physiology laboratory study the molecular strategies developed by microalgae​ that allow them to have a selective growth advantage in low light conditions. This study suggests ways to improve their growth in the case of future applications in biotechnology.​ References Allorent G, Tokutsu R, Roach T, Peers G, Cardol P, Girard-Bascou J, Seigneurin-Berny D, Petroutsos D, Kuntz M, Breyton C, Franck F, Wollman FA, Niyogi KK, Krieger-Liszkay A, Minagawa J and Finazzi G A dual strategy to cope with high light in Chlamydomonas reinhardtii. Plant Cell, 2013
21st December 2010

Genomic insights into photosynthesis in eukaryotic phytoplankton

Researchers at the Cell & Plant Physiology laboratory decided to explore the role of state transitions on photosynthesis in Chlamydomonas mutants with respiratory defects. The analysis of these mutants has allowed them to show the essential role of the role of state transitions on photosynthesis of the green alga Chlamydomonas. References Bailleul B, Rogato A, de Martino A, Coesel S, Cardol P, Bowler C, Falciatore A and Finazzi G An atypical member of the light-harvesting complex stress-related protein family modulates diatom responses to light. Proceedings of the National Academy of Sciences USA
13th December 2010

Diatoms and light

Researchers at the Cell & Plant Physiology laboratory have identified a key component of the photo-accli​mation mechanisms of a diatom that allows it to acclimate to changes in its environmental conditions, especially fluctuations of the light intensity. References Bailleul B, Rogato A, de Martino A, Coesel S, Cardol P, Bowler C, Falciatore A and Finazzi G An atypical member of the light-harvesting complex stress-related protein family modulates diatom responses to light. Proceedings of the National Academy of Sciences, USA, 2010
29th May 2009

Draw inspiration from plants to better control our energy and material flows

Living organisms have developed regulatory systems of their metabolic pathways, which they need to survive. Why not learn from these mechanisms to improve our control of material flow and energy ? It is in this context that researchers from CNRS, INRA and CEA have developed a mathematical model representing the amino acid biosynthetic pathways in the plant Arabidopsis. This model was used to reproduce the measurements made with whole plants, thus demonstrating its accuracy. Simulations were then allowed to qualitatively and quantitatively understand the operation of such a control network. References Curien G, Bastien O, Robert-Genthon M, Cornish-Bowden A, Cárdenas […]
8th May 2008

An original adaptation of photosynthesis in the marine green alga Ostreococcus

The analysis of the adaptation of different ecotypes of Ostreococcus (a green line picoeucaryote) belonging to two different ecological niches both in their nutrient content (Fe) and light gave unexpected results.​ References Cardol P, Bailleul B, Rappaport F, Derelle E, Béal D, Breyton C, Bailey S, Wollman FA, Grossman A, Moreau H and Finazzi G An original adaptation of photosynthesis in the marine green alga Ostreococcus. Proceedings of the National Academy of Sciences USA, 2008