Biography
of Dr. Dimitris Petroutsos


Dimitris Petroutsos

Light, Photosynthesis & Metabolism (LP&M) Team Leader,
PhD, Researcher CNRS

CEA-Grenoble
17 avenue des Martyrs, 38 054 Grenoble cedex 09, France
Phone: +33 (0) 438 786 663
Fax: +33 (0) 438 785 091

BIG / PCV / LPM, Center : Grenoble / DSV

RESEARCH INTERESTS

Photosynthetic microalgae are fascinating organisms that thrive in both freshwater and oceanic waters but also on the soil. They use the energy from sunlight to generate the chemical energy needed to fix CO2 releasing at the same time O2. In their everyday life microalgae are exposed to a wide range of abiotic stresses: from anthropogenic xenobiotics to nutrient or oxygen limitation or exposure to high intensity light. In all cases the cells need to maintain their homeostasis and for that complicated cellular mechanisms have evolved that provide protection and stress tolerance. Throughout my research, I have been interested in identifying the molecular mechanisms that photosynthetic microalgae employ to respond to different types of abiotic stresses. Presently I have been focusing on better understanding the complex interconnection of photoreception, photosynthesis and metabolism within Chlamydomonas reinhardtii.

Research experience

  • 2014/Present
    CNRS Researcher (CR1)
    Laboratory of Cell & Plant Physiology, Research Institute of Life Sciences and Technologies French National Center of Scientific Research (CNRS), CEA-Grenoble, Grenoble, France.
  • 2012-2014
    Post Doctoral Researcher
    Laboratory of Cell & Plant Physiology, Research Institute of Life Sciences and Technologies French National Center of Scientific Research (CNRS), CEA-Grenoble, Grenoble, France.
  • 2007-2012
    Post Doctoral Researcher
    University of Münster, Department of Plant Biology and Biotechnology, Muenster, Germany. 2006.
  • 2006
    Visiting PhD Student (9 months)
    Arizona State University, Laboratory of Algae Research, Department of Applied Biological Sciences, Mesa, Arizona, USA.

Education

  • 2007
    Ph.D. in Chemical Engineering (Algal Biotechnology)
    National Technical University of Athens, Biotechnology Laboratory, School of Chemical Engineering, Athens, Greece.
  • 1999
    Five-year Degree in Chemical Engineering
    National Technical University of Athens, School of Chemical Engineering, Athens, Greece.

Patents

Conte M, Dolch L-J, Mei C, Barette C, Petroutsos D, Falconet D, Jouhet J, Rébeillé F, Cintrat JC, Maréchal E. Inhibitors of sterol metabolism for their use to accumulate triglycerides in microalgae, and methods thereof. 2015, WO2015111029 A1

Conferences/ Oral presentations
Poster presentations/ Research grants

See CV in pdf format.

Publications

Petroutsos D*, Tokutsu R, Maruyama S, Flori S, Greiner A, Magneschi L, Cusant L, Kottke T, Mittag M, Hegemann P, Finazzi G* and Minagawa J*
A blue-light photoreceptor mediates the feedback regulation of photosynthesis.
Nature, 2016, 537(7621): 563-566

Hochmal AK, Zinzius K, Charoenwattanasatien R, Gäbelein P, Mutoh R, Tanaka H, Schulze S, Liu G, Scholz M, Nordhues A, Offenborn JN, Petroutsos D, Finazzi G, Fufezan C, Huang K, Kurisu G and Hippler M
Calredoxin represents a novel type of calcium-dependent sensor-responder connected to redox regulation in the chloroplast.
Nature Communications, 2016, 7: 11847

Curien G, Flori S, Villanova V, Magneschi L, Giustini C, Forti G, Matringe M, Petroutsos D, Kuntz M and Finazzi G
The water to water cycles in microalgae.
Plant and Cell Physiology, 2016, 57(7): 1354-1363

Bailleul B, Berne N, Murik O, Petroutsos D, Prihoda J, Tanaka A, Villanova V, Bligny R, Flori S, Falconet D, Krieger-Liszkay A, Santabarbara S, Rappaport F, Joliot P, Tirichine L, Falkowski PG, Cardol P, Bowler C and Finazzi G
Energetic coupling between plastids and mitochondria drives CO assimilation in diatoms.
Nature, 2015, 524(7565): 366-369

Abida H, Dolch LJ, Meï C, Villanova V, Conte M, Block MA, Finazzi G, Bastien O, Tirichine L, Bowler C, Rébeillé F, Petroutsos D*, Jouhet J* and Maréchal E*
Membrane glycerolipid remodeling triggered by nitrogen and phosphorus starvation in Phaeodactylum tricornutum.
Plant Physiology, 2015, 167(1): 118-136

Finazzi G, Petroutsos D, Tomizioli M, Flori S, Sautron E, Villanova V, Rolland N and Seigneurin-Berny D
Ions channels/transporters and chloroplast regulation.
Cell Calcium, 2015, 58(1): 86–97

Nagy G, Unnep R, Zsiros O, Tokutsu R, Takizawa K, Porcar L, Moyet L, Petroutsos D, Garab G, Finazzi G and Minagawa J
Chloroplast remodeling during state transitions in Chlamydomonas reinhardtii as revealed by non-invasive techniques in vivo.
Proceedings of the National Academy of Sciences USA, 2014, 111(13): 5042-5047

Kukuczka B, Magneschi L, Petroutsos D, Steinbeck J, Bald T, Powikrowska M, Fufezan C, Finazzi G and Hippler M
Proton gradient regulation5-like1-mediated cyclic electron flow is crucial for acclimation to anoxia and complementary to nonphotochemical quenching in stress adaptation.
Plant Physiology, 2014, 165(4): 1604-1617

Johnson X, Steinbeck J, Dent R, Richaud P, Ozawa S-I, Houille-Vernes L, Petroutsos D, Rappaport F, Grossman AR, Niyogi KK, Hippler M and Alric J
Proton gradient regulated 5-mediated cyclic electron flow under ATP- or redox- limiting conditions: A study of pgr5 ΔATPase and pgr5 ΔrbcL mutants in Chlamydomonas reinhardtii.
Plant Physiology, 2014, 165(1): 438-452

Petroutsos D, Amiar S, Abida H, Dolch LJ, Bastien O, Rébeillé F, Jouhet J, Falconet D, Block MA, McFadden GI, Bowler C, Botté C and Maréchal E Evolution of galactoglycerolipid biosynthetic pathways. From cyanobacteria to primary plastids and from primary to secondary plastids.
Progress in Lipid Research, 2014, 54C: 68-85

Boudière L, Michaud M, Petroutsos D, Rébeillé F, Falconet D, Bastien O, Roy S, Finazzi G, Rolland N, Jouhet J, Block MA and Maréchal E
Glycerolipids in photosynthesis: Composition, synthesis and trafficking.
Biochimica and Biophysica Acta, 2014, 1837(2): 470-480

Allorent G, Tokutsu R, Roach T, Peers G, Cardol P, Girard-Bascou J, Seigneurin-Berny D, Petroutsos D, Kuntz M, Breyton C, Franck F, Wollman FA, Niyogi KK, Krieger-Liszkay A, Minagawa J and Finazzi G
A dual strategy to cope with high light in Chlamydomonas reinhardtii.
Plant Cell, 2013, 25(2): 545-557

Terashima M, Petroutsos D*, Hudig M, Tolstygina I, Trompelt K, Gabelein P, Fufezan C, Kudla J, Weinl S, Finazzi G and Hippler M
Calcium-dependent regulation of cyclic photosynthetic electron transfer by a CAS, ANR1, and PGRL1 complex.
Proceedings of the National Academy of Sciences, 2012, 109(43): 17717-17722
(* equally contributed authors)

Petroutsos D, Busch A, Janssen I, Trompelt K, Bergner SV, Weinl S, Holtkamp M, Karst U, Kudla J and Hippler M
The chloroplast calcium sensor CAS is required for photoacclimation in Chlamydomonas reinhardtii.
Plant Cell, 2011, 23(8): 2950-2963

Mamma D, Papadopoulou E, Petroutsos D, Christakopoulos P and Kekos D
Removal of 1,3-dichloro2-propanol and 3-chloro1,2-propanediol by the whole cell system of Pseudomonas putida DSM 437.
Journal of Environmental Science and Health A Toxic/ Hazardous Substances & Environmental Engineering, 2006, 41(3): 303–313

Petroutsos D, Katapodis P, Christakopoulos P and Kekos D
Removal of p-chlorophenol by the marine microalga Tetraselmis marina.
Journal of Applied Phycology, 2007, 485–490

Petroutsos D, Wang J, Katapodis P, Kekos D, Sommerfeld M and Hu Q
Toxicity and metabolism of p-chlorophenol in the marine microalga Tetraselmis marina.
Aquatic Toxicology, 2007, 85(3): 192–201

Petroutsos D, Katapodis P, Samiotaki M, Panayotou G and Kekos D
Detoxification of 2,4-dichlorophenol by the marine microalga Tetraselmis marina.
Phytochemistry, 2008, 69(3): 707–714

Panagiotou G, Pachidou F, Petroutsos D, Olsson L and Christakopoulos P
Fermentation characteristics of Fusarium oxysporum grown on acetate.
Bioresource Technology, 2008, 99(15): 7397–7401

Petroutsos D, Terauchi AM, Busch A, Hirschmann I, Merchant SS, Finazzi G and Hippler M
PGRL1 participates in iron-induced remodeling of the photosynthetic apparatus and in energy metabolism in Chlamydomonas reinhardtii.
Journal of Biological Chemistry, 2009, 284(47): 32770–32781

Tolleter D, Ghysels B, Alric J, Petroutsos D, Tolstygina I, Krawietz D, Happe T, Auroy P, Adriano JM, Beyly A, Cuine S, Plet J, Reiter IM, Genty B, Cournac L, Hippler M and Peltier G
Control of hydrogen photoproduction by the proton gradient generated by cyclic electron flow in Chlamydomonas reinhardtii.
The Plant Cell, 2011, 23(7): 2619–2630

*corresponding author